Job description

We are 2 Translational Research Groups at “Hospital Universitario 12 de Octubre” (Madrid) led by Dr. Elena Castro, MD PhD, (Translational Cancer genetics) and Dr. David Olmos, MD PhD, (Prostate Cancer Genomics and Therapeutics). We work closely on several projects as a multidisciplinary team within the Genitourinary Cancer Program. Our projects aim to unlock the potential of LP-WGS, WES, and genetic panels to find new prognostic and predictive markers in prostate cancer. These 2 research groups are integrated in the Medical Oncology Department at Hospital Universitario 12 de Octubre (H12O) led by Prof. Luis Paz-Ares.

We seek a highly motivated Computer Engineer or Informatics Engineer to join our labs. The candidate should have the required computational skills to provide crucial support to our researchers. The role will primarily involve maintaining and managing our resource data in the High-Performance Computing (HPC) cluster, maintaining and managing databases, and ensuring the smooth operation of our variant calling pipeline.

We generate massive amounts of genomic data from cohorts of cancer patients from our clinical projects and perform variant calling and variant interpretation to identify new biomarkers.

What do we offer?

We offer a two-year funded position with the possibility to extend this tenure according to results and career aims.

We offer a competitive salary according to institutional scale.

Key Responsibilities:

 -  HPC Cluster Management:

•   Maintain and optimize the performance of our High-Performance Computing Cluster.
•   Troubleshoot and resolve issues to ensure uninterrupted computational support for our research projects.

 -  Database Management:

•   Manage and maintain our database systems, with a strong emphasis on SQL.
•   Ensure data integrity, security, and efficient retrieval for our researchers.

 -  Pipeline managing:

•   Support our research team to improve and automate data processing.

 -  Technical Support:

•   Provide technical assistance and guidance to researchers regarding computational resources, software tools, and data management.

 -  Hardware Support:

•   Provide technical support for the maintenance and acquisition of informatic equipment.

 - Collaboration:

•   Collaborate with cross-functional teams to understand the computational needs of ongoing research projects and adapt systems accordingly.

Candidate Profile – Selection Criteria

Titles

- Bachelor or diploma in Technical Computer Engineering, Computer Engineering, Informatics Engineering, or a related field.

- Optional MSc in Computer Engineering, Informatics, or Computational Sciences.

Experience

- ESSENTIAL: Strong background in informatics and computer science.

- At least 2 years of experience.

Technical Skills

- Analytical skills and problem-solving abilities.

- Practical experience in managing HPC cluster environments. Proficiency in database management, with a focus on SQL. Experience with data management and processing.

- Experience with GNU/Linux cluster environments and experience using scripting and programming languages such as Java, Perl, Python, or Shell script. Optional experience in bioinformatics toolkits such as BioPerl and Bioconductor (within the R statistical programming environment).

- Database managing and developing. Relational and non-relational databases (SQL knowledge).

- Excellent communication and teamwork skills.

Languages

- Basic English level (speaking and writing).

- Spanish is not essential but it should be valued.

Those interested should send their CV to prosinfo23@prostatelab.net with the subject PROSINFO23-02.