The Gene Regulation Lab, an ICREA group at the IDIBAPS Research Institute (Barcelona, Spain), is looking for a postdoc to work on the role of the plasticity EMT factors ZEB1 and ZEB2 in macrophages during cancer (tumor-associated macrophages in colorectal cancer, ovarian cancer, melanoma). The ZEB1 and ZEB1  factors play key roles in homeostasis and disease regulating stemness (normal/cancer stem cells), differentiation, tissue regeneration, and tumor initiation and progression. 

The successful candidates will join a dynamic and international group of postdoc and PhD students in a leading research center in downtown Barcelona.

The projects  make use of a wide array of state-of-the-art techniques, and in vitro and in vivo approaches including unique transgenic mouse models and high-throughput and OMICs technologies. 

REQUIREMENTS

Essential Requirements 

★ PhD degree in Biology or related bio- medical discipline obtained not earlier than January 2019. 

★ Strong publication record with at least 2-3 first-author articles in high impact journals 

★ Solid background in Molecular and Cellular Biology. 

★ Experience in mouse models

Desirable Experience 

Candidates with proven experience in any of the following topics will receive higher consideration in the selection process: macrophage biology (acute/chronic inflammation, cancer) molecular oncology, metabolism, epigenetics, transcriptomics, and/or bioinformatics.

CONDITIONS 

The positions are available immediately. The salary will be commensurate with the expertise and the publication record.

ADDITIONAL INFORMATION & APPLICATIONS 

For further information about the work in the group visit https://bit.ly/34r2VXT & https://bit.ly/3zWD3DG Applications should include: a) complete CV, b) the names and contact details of three researchers that have supervised the candidate’s work. Additional inquiries and applications should be sent to: idibaps.postigo3@gmail.com indicating “Postdoc Call TAMs 2021” in the subject of the email. 

SELECTED PUBLICATIONS 

(recent articles as corresponding author)

★ Gut 66:666. IF: 23.0

★ Gut 68:2129. IF: 23.0

★ Nature Commun 10:1364. IF: 14.9

★ Nature Commun 9:2424. IF: 14.9

 ★ Nature Commun 5:5660. IF: 14.9

 ★ Nature Commun 4:2650. IF: 14.9 

★ Sci Advances 7:abd7455 IF: 14.1 

★ Nucleic Acids Res 46:10697. IF: 16.9

 ★ Cell Death Differ 21:247. IF:15.8

★ Clin Cancer Res 19:1071. IF: 12.7 

★ EMBO J 36:3336. IF: 11.6